Antibacterial properties of nanoparticles

被引：1967

作者：

Hajipour, Mohammad J. ^{[1
]}

Fromm, Katharina M. ^{[2
]}

Ashkarran, Ali Akbar ^{[3
]}

Jimenez de Aberasturi, Dorleta ^{[4
,5
,8
]}

Ruiz de Larramendi, Idoia ^{[5
]}

Rojo, Teofilo ^{[5
]}

Serpooshan, Vahid ^{[6
]}

Parak, Wolfgang J. ^{[4
,8
]}

Mahmoudi, Morteza ^{[1
,7
]}

机构：

[1] Univ Tehran Med Sci, Fac Pharm, Dept Nanotechnol, Lab NanoBio Interact, Tehran, Iran

[2] Univ Fribourg, Dept Chem, CH-1700 Fribourg, Switzerland

[3] Univ Mazandaran, Fac Basic Sci, Dept Phys, Babol Sar, Iran

[4] Univ Marburg, Fachbereich Phys, Marburg, Germany

[5] Univ Basque Country, Dept Inorgan Chem, Bilbao, Spain

[6] Stanford Univ, Sch Med, Dept Pediat, Div Pediat Cardiol, Stanford, CA 94305 USA

[7] Univ Tehran Med Sci, Fac Pharm, Nanotechnol Res Ctr, Tehran, Iran

[8] Univ Marburg, WZMW, Marburg, Germany

来源：

TRENDS IN BIOTECHNOLOGY | 2012年 / 30卷 / 10期

关键词：

antibacterial agent; nanoparticle; toxicity; SILVER NANOPARTICLES; ESCHERICHIA-COLI; NITRIC-OXIDE; MAGNETIC NANOPARTICLES; BACTERIAL BIOFILMS; TOXICITY; RESISTANCE; TIO2; ZNO; ANTIBIOTICS;

D O I：

10.1016/j.tibtech.2012.06.004

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Antibacterial agents are very important in the textile industry, water disinfection, medicine, and food packaging. Organic compounds used for disinfection have some disadvantages, including toxicity to the human body, therefore, the interest in inorganic disinfectants such as metal oxide nanoparticles (NPs) is increasing. This review focuses on the properties and applications of inorganic nanostructured materials and their surface modifications, with good antimicrobial activity. Such improved antibacterial agents locally destroy bacteria, without being toxic to the surrounding tissue. We also provide an overview of opportunities and risks of using NPs as antibacterial agents. In particular, we discuss the role of different NP materials.

引用

页码：499 / 511

页数：13

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