Umbilical cord blood procalcitonin and C reactive protein concentrations as markers for early diagnosis of very early onset neonatal infection

被引:63
作者
Joram, N
Boscher, C
Denizot, S
Loubersac, V
Winer, N
Roze, JC
Gras-Le Guen, C
机构
[1] CHU Nantes, Dept Perinatol, Hop Mere Enfant, F-44000 Nantes, France
[2] Biochim Lab, Nantes, France
[3] Hop Mere Enfant, Serv Gynecol Obstet, Nantes, France
[4] Fac Med, Lab Antibiol, Nantes, France
来源
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION | 2006年 / 91卷 / 01期
关键词
D O I
10.1136/adc.2005.074245
中图分类号
R72 [儿科学];
学科分类号
100202 [儿科学];
摘要
Procalcitonin (PCT) and C reactive protein (CRP) concentrations in umbilical cord blood of 197 neonates were measured to evaluate their value as markers of infection. Sixteen of the neonates were infected. The sensitivity, specificity, and negative and positive predictive values were respectively 87.5%, 98.7%, 87.5%, and 98.7% for PCT and 50%, 97%, 67%, and 94% for CRP. Serum PCT in cord blood seems to be a useful and early marker of antenatal infection.
引用
收藏
页码:F65 / F66
页数:2
相关论文
共 5 条
[1]
Reliability of procalcitonin concentrations for the diagnosis of sepsis in critically ill neonates [J].
Chiesa, C ;
Panero, A ;
Rossi, N ;
Stegagno, M ;
De Giusti, M ;
Osborn, JF ;
Pacifico, L .
CLINICAL INFECTIOUS DISEASES, 1998, 26 (03) :664-672
[2]
Procalcitonin as a marker for the early diagnosis of neonatal infection [J].
Gendrel, D ;
Assicot, M ;
Raymond, J ;
Moulin, F ;
Francoual, C ;
Badoual, J ;
Bohuon, C .
JOURNAL OF PEDIATRICS, 1996, 128 (04) :570-573
[3]
Lack of specificity of procalcitonin for sepsis diagnosis in premature infants [J].
Lapillonne, A ;
Basson, E ;
Monneret, G ;
Bienvenu, J ;
Salle, BL .
LANCET, 1998, 351 (9110) :1211-1212
[4]
DIAGNOSTIC AUDIT OF C-REACTIVE PROTEIN IN NEONATAL INFECTION [J].
MATHERS, NJ ;
POHLANDT, F .
EUROPEAN JOURNAL OF PEDIATRICS, 1987, 146 (02) :147-151
[5]
Sachse C, 1998, CLIN CHEM, V44, P1343