The Brussels Declaration: the need for change in asthma management

被引:85
作者
Holgate, S. [1 ]
Bisgaard, H. [4 ]
Bjermer, L. [5 ]
Haahtela, T. [6 ]
Haughney, J. [2 ]
Horne, R. [3 ]
McIvor, A. [8 ]
Palkonen, S. [9 ]
Price, D. B. [2 ]
Thomas, M. [2 ]
Valovirta, E. [7 ]
Wahn, U. [10 ]
机构
[1] Univ Southampton, Southampton Gen Hosp, Infect Inflammat & Repair AIR Div, Southampton SO16 6YD, Hants, England
[2] Univ Aberdeen, Dept Gen Practice & Primary Care, Aberdeen AB9 1FX, Scotland
[3] Univ London, Sch Pharm, Ctr Behav Med, London WC1N 1AX, England
[4] Univ Copenhagen, Dept Pediat, Copenhagen, Denmark
[5] Lund Univ, Dept Med & Allergol, Lund, Sweden
[6] Helsinki Univ Hosp, Dept Allergy Skin & Allergy Hosp, Helsinki, Finland
[7] Finnish Soc Paediat, Helsinki, Finland
[8] McMaster Univ, Firestone Inst Resp Hlth, Hamilton, ON, Canada
[9] European Fed Allergy & Airway Dis Patients Assoc, Execut Off, Brussels, Belgium
[10] Charite, Dept Med, D-13353 Berlin, Germany
基金
英国医学研究理事会;
关键词
Asthma; management; the Brussels Declaration;
D O I
10.1183/09031936.00053108
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Asthma is a highly prevalent condition across Europe and numerous guidelines have been developed to optimise management. However, asthma can be neither cured nor prevented, treatment choices are limited and many patients have poorly controlled or uncontrolled asthma. The Brussels Declaration on Asthma, sponsored by The Asthma, Allergy and Inflammation Research Charity, was developed to call attention to the shortfalls in asthma management and to urge European policy makers to recognise that asthma is a public health problem that should be a political priority. The Declaration urges recognition and action on the following points: the systemic Inflammatory component of asthma should be better understood and considered in assessments of treatment efficacy; current research must be communicated and responded to quickly; the European Medicines Agency guidance note on asthma should be updated; "real world" studies should be funded and results used to Inform guidelines; variations in care across Europe should be addressed; people with asthma should participate in their own care; the impact of environmental factors should be understood; and targets should be set for improvement. The present paper reviews the evidence supporting the need for change in asthma management and summarises the ten key points contained In the Brussels Declaration.
引用
收藏
页码:1433 / 1442
页数:10
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