Calcitonin gene-related peptide: Vasoactive effects and potential therapeutic role

被引:81
作者
Brain, SD [1 ]
Cambridge, H [1 ]
机构
[1] UNIV LONDON KINGS COLL,VASC BIOL RES CTR,LONDON SW3 6LX,ENGLAND
来源
GENERAL PHARMACOLOGY | 1996年 / 27卷 / 04期
关键词
calcitonin gene-related peptide; CGRP; cardiovascular; microvascular; vascular;
D O I
10.1016/0306-3623(95)00125-5
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
1. The cardiovascular biology of calcitonin gene related peptide (CORP) and the structurally related peptides amylin and adrenomedullin are briefly reviewed. 2. CGRP is a potent and long lasting vasodilator; its possible role in disease, and the therapeutic potential of CORP receptor agonists and antagonists is discussed.
引用
收藏
页码:607 / 611
页数:5
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