Nigral endothelial dysfunction, homocysteine, and Parkinson's disease

被引：111

作者：

Müller, T

Werne, B

Fowler, B

Kuhn, W

机构：

[1] Ruhr Univ Bochum, St Josef Hosp, Dept Neurol, D-44791 Bochum, Germany

[2] Univ Childrens Hosp, Basel, Switzerland

来源：

LANCET | 1999年 / 354卷 / 9173期

关键词：

D O I：

10.1016/S0140-6736(99)01660-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We found increased levels of atherosclerosis-inducing homocysteine in parkinsonian patients with long-term application of levodopa compared with previously untreated parkinsonian patients and controls. We conclude that antiparkinsonian treatment with levodopa promotes occurrence of vascular disease in Parkinson's disease.

引用

页码：126 / 127

页数：2

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