Nanoporous protein particles through templating mesoporous silica spheres

被引:98
作者
Wang, YJ [1 ]
Caruso, F [1 ]
机构
[1] Univ Melbourne, Ctr Nanosci & Nanotechnol, Dept Chem & Biomol Engn, Melbourne, Vic 3010, Australia
关键词
D O I
10.1002/adma.200501901
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Sequential assembly of protein and polyelectrolyte in mesoporous silica (MS) spheres leads to the formation of nanoporous protein particles (NPPs); the MS templates are removed after the fabrication process (see figure). The NPPs based on catalase show excellent biological activity, with up to 57 % of the activity retained. This strategy offers a novel and effective method of preparing bioactive NPPs of diverse composition, particle size, and shape.
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页码:795 / +
页数:7
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