Valproate therapy and nonalcoholic fatty liver disease

被引：75

作者：

Luef, GJ

Waldmann, M

Sturm, W

Naser, A

Trinka, E

Unterberger, I

Bauer, G

Lechleitner, M

机构：

[1] Univ Innsbruck Hosp, Dept Neurol, A-6020 Innsbruck, Austria

[2] Univ Innsbruck Hosp, Dept Internal Med, A-6020 Innsbruck, Austria

来源：

ANNALS OF NEUROLOGY | 2004年 / 55卷 / 05期

关键词：

D O I：

10.1002/ana.20074

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Nonalcoholic fatty liver disease was defined recently as another symptom of insulin resistance. Continuous therapy with valproate can result in increased body weight and insulin resistance, but no data are yet available on a possible relationship between valproate and nonalcoholic fatty liver disease. We here demonstrate in abdominal ultrasound investigations that characteristics of fatty liver disease were present in 61% of valproate-treated patients as compared with 23% receiving carbamazepine therapy.

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页码：729 / 732

页数：4

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