Crystal structure of human estrogenic 17 beta-hydroxysteroid dehydrogenase complexed with 17 beta-estradiol

被引：141

作者：

Azzi, A

Rehse, PH

Zhu, DW

Campbell, RL

Labrie, F

Lin, SX

机构：

[1] CHU LAVAL,MRC,GRP MOL ENDOCRINOL,QUEBEC CITY,PQ G1V 4G2,CANADA

[2] UNIV LAVAL,QUEBEC CITY,PQ G1V 4G2,CANADA

来源：

NATURE STRUCTURAL BIOLOGY | 1996年 / 3卷 / 08期

关键词：

D O I：

10.1038/nsb0896-665

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Estrogenic 17 beta-hydroxysteroid dehydrogenase may promote tumour growth in some breast carcinomas. The 2.3 Angstrom structure of the human enzyme Complexed with 17 beta-estradiol gives insight into the specificity of substrate binding.

引用

页码：665 / 668

页数：4

共 23 条

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