Interendothelial junctions: structure, signalling and functional roles

被引：187

作者：

Lampugnani, MG

Dejana, E

机构：

[1] Vascular Biology Laboratory, Mario Negri Inst. Pharmacol. Res.

来源：

CURRENT OPINION IN CELL BIOLOGY | 1997年 / 9卷 / 05期

关键词：

D O I：

10.1016/S0955-0674(97)80121-4

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Endothelial cell-cell adhesive junctions are formed by transmembrane adhesive proteins linked to a complex cytoskeletal network. These structures are important not only for maintaining adhesion between endothelial cells and, as a consequence, for the control of vascular permeability, but also for intracellular signalling properties. The establishment of intercellular junctions might affect the endothelial functional phenotype by the downregulation or upregulation of endothelial-specific activities.

引用

收藏

页码：674 / 682

页数：9

相关论文

共 95 条

[1]

Aberle H, 1996, J CELL BIOCHEM, V61, P514, DOI 10.1002/(SICI)1097-4644(19960616)61:4<514::AID-JCB4>3.0.CO

[2]

2-R

[3] A nuclear protein regulated during the transition from active to quiescent phenotype in cultured endothelial cells [J].

Alliegro, MC ;

Alliegro, MA .

DEVELOPMENTAL BIOLOGY, 1996, 174 (02) :288-297

[4] TIGHT JUNCTIONS AND THE MOLECULAR-BASIS FOR REGULATION OF PARACELLULAR PERMEABILITY [J].

ANDERSON, JM ;

VANITALLIE, CM .

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 1995, 269 (04) :G467-G475

[5] CHARACTERIZATION OF ZO-1, A PROTEIN-COMPONENT OF THE TIGHT JUNCTION FROM MOUSE-LIVER AND MADIN-DARBY CANINE KIDNEY-CELLS [J].

ANDERSON, JM ;

STEVENSON, BR ;

JESAITIS, LA ;

GOODENOUGH, DA ;

MOOSEKER, MS .

JOURNAL OF CELL BIOLOGY, 1988, 106 (04) :1141-1149

[6] DENSITY-DEPENDENT EXPRESSION OF HYALURONIC-ACID BINDING TO VASCULAR CELLS-INVITRO [J].

ANTONELLI, A ;

DAMORE, PA .

MICROVASCULAR RESEARCH, 1991, 41 (02) :239-251

[7] MIGRATING ENDOTHELIAL-CELLS ARE DISTINCTLY HYPERGLYCOSYLATED AND EXPRESS SPECIFIC MIGRATION-ASSOCIATED CELL-SURFACE GLYCOPROTEINS [J].

AUGUSTINVOSS, HG ;

PAULI, BU .

JOURNAL OF CELL BIOLOGY, 1992, 119 (02) :483-491

[8] 2 CLASSES OF TIGHT JUNCTIONS ARE REVEALED BY ZO-1 ISOFORMS [J].

BALDA, MS ;

ANDERSON, JM .

AMERICAN JOURNAL OF PHYSIOLOGY, 1993, 264 (04) :C918-C923

[9] The SH3 domain of the tight junction protein ZO-1 binds to a serine protein kinase that phosphorylates a region C-terminal to this domain [J].

Balda, MS ;

Anderson, JM ;

Matter, K .

FEBS LETTERS, 1996, 399 (03) :326-332

[10] Regulated binding of a PTP1B-like phosphatase to N-cadherin: Control of cadherin-mediated adhesion by dephosphorylation of beta-catenin [J].

Balsamo, J ;

Leung, TC ;

Ernst, H ;

Zanin, MKB ;

Hoffman, S ;

Lilien, J .

JOURNAL OF CELL BIOLOGY, 1996, 134 (03) :801-813

← 1 2 3 4 5 6 7 8 9 10 →