Mammalian Cells Change Volume during Mitosis

被引：69

作者：

Boucrot, Emmanuel ^{[1
]}

Kirchhausen, Tomas ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA

来源：

PLOS ONE | 2008年 / 3卷 / 01期

关键词：

D O I：

10.1371/journal.pone.0001477

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Using single cell-imaging methods we have found that the volume of adherent cells grown in culture decreases as the cells rounds when it enters mitosis. A minimal volume is reached at metaphase. Rapid volume recovery initiates before abscission as cells make the transition from metaphase to cytokinesis. These volume changes are simultaneous with the rapid surface area decrease and recovery observed in mitotic cells [1].

引用

页数：3

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