In vitro activity of a new pneumocandin antifungal, L-743,872, against azole-susceptible and -resistant Candida species

被引：90

作者：

Vazquez, JA ^{[1
]}

Lynch, M ^{[1
]}

Boikov, D ^{[1
]}

Sobel, JD ^{[1
]}

机构：

[1] VET ADM MED CTR,DETROIT,MI

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1997年 / 41卷 / 07期

关键词：

D O I：

10.1128/AAC.41.7.1612

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The in vitro activity of a new pneumocandin, L-743,872, was evaluated with 108 strains of Candida and compared with the activities of various antifungals. L-743,872 demonstrated the best activity against azole-susceptible and -resistant strains of C. albicans, C. glabrata, C. tropicalis, C. parapsilosis, and C. kefyr and less activity against C. krusei, C. lusitaniae, and C. guilliermondii.

引用

页码：1612 / 1614

页数：3

共 11 条

[1] SECULAR TRENDS IN NOSOCOMIAL PRIMARY BLOOD-STREAM INFECTIONS IN THE UNITED-STATES, 1980-1989
BANERJEE, SN
EMORI, TG
CULVER, DH
GAYNES, RP
JARVIS, WR
HORAN, T
EDWARDS, JR
TOLSON, J
HENDERSON, T
MARTONE, WJ
[J]. AMERICAN JOURNAL OF MEDICINE, 1991, 91 : S86 - S89
[2] BECKSAGUE CM, 1993, J INFECT DIS, V167, P1247, DOI 10.1093/infdis/167.5.1247
[3] BODEY GP, 1986, AM J MED S4D, V77, P13
[4] SYNTHESIS AND ANTIFUNGAL ACTIVITY OF NOVEL CATIONIC PNEUMOCANDIN B-O DERIVATIVES
BOUFFARD, FA
ZAMBIAS, RA
DROPINSKI, JF
BALKOVEC, JM
HAMMOND, ML
ABRUZZO, GK
BARTIZAL, KF
MARRINAN, JA
KURTZ, MB
MCFADDEN, DC
NOLLSTADT, KH
POWLES, MA
SCHMATZ, DM
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1994, 37 (02) : 222 - 225
[5] CABIB E, 1987, METHOD ENZYMOL, V138, P637
[6] CASSONE A, 1981, SABOURAUDIA, V19, P97
[7] COLLABORATIVE COMPARISON OF BROTH MACRODILUTION AND MICRODILUTION ANTIFUNGAL SUSCEPTIBILITY TESTS
ESPINELINGROFF, A
KISH, CW
KERKERING, TM
FROMTLING, RA
BARTIZAL, K
GALGIANI, JN
VILLAREAL, K
PFALLER, MA
GERARDEN, T
RINALDI, MG
FOTHERGILL, A
[J]. JOURNAL OF CLINICAL MICROBIOLOGY, 1992, 30 (12) : 3138 - 3145
[8] ECHINOCANDIN INHIBITION OF 1,3-BETA-D-GLUCAN SYNTHASE FROM CANDIDA-ALBICANS
SAWISTOWSKASCHRODER, ET
KERRIDGE, D
PERRY, H
[J]. FEBS LETTERS, 1984, 173 (01) : 134 - 138
[9] Shadomy S., 1991, MANUAL CLIN MICROBIO, P1173
[10] WARNOCK DW, 1988, LANCET, V1, P1310

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