In vivo cleavage of a target RNA by copper kanamycin A.: Direct observation by a fluorescence assay

被引：31

作者：

Chen, CA ^{[1
]}

Cowan, JA ^{[1
]}

机构：

[1] Ohio State Univ, Evans Lab Chem, Columbus, OH 43210 USA

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 03期

关键词：

D O I：

10.1039/b108439a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel fluorescence assay to monitor in vivo cleavage chemistry of RNA target sequences has been established and used to demonstrate the activity of copper aminoglycoside mediated degradation of RNA in bacterial cells.

引用

页码：196 / 197

页数：2

共 16 条

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