Topiramate weight loss in migraine patients

被引：15

作者：

Alberici, Antonella ^{[1
]}

Borroni, Barbara

Manelli, Filippo ^{[2
]}

Griffini, Simona ^{[3
]}

Zavarise, Paola ^{[3
]}

Padovani, Alessandro

Volta, Giorgio Dalla ^{[3
]}

机构：

[1] Univ Brescia, Dept Med & Surg Sci, Neurol Unit, I-25100 Brescia, Italy

[2] Spedali Civil Brescia, Emergency Unit, I-25125 Brescia, Italy

[3] San Donato Grp, ICCB, Neurol Unit, Brescia, Italy

来源：

JOURNAL OF THE NEUROLOGICAL SCIENCES | 2009年 / 278卷 / 1-2期

关键词：

Migraine; Topiramate; Weight loss; Body mass index (BMI); CONTROLLED-TRIAL; DOUBLE-BLIND; PREVENTION;

D O I：

10.1016/j.jns.2008.11.014

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

100204 [神经病学];

摘要：

Topiramate (TPM) is generally recognized efficacious and safe in migraine prevention. A significant proportion of patients undergoing TPM administration may show weight loss. In epileptic subjects, high body mass index (BMI) was found to be predictive of weight loss under TPM therapy. We therefore aimed to study whether common clinical determinants may be associated to TPM weigh loss in migraine patients. In our clinical series, high BMI was not found a predictor of weight loss under TPM treatment. Unknown genetic and environmental factors that may determine the courses of weight loss under TPM therapy are still do be identified. (c) 2008 Elsevier B.V. All rights reserved.

引用

页码：64 / 65

页数：2

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