Autologous mononuclear bone marrow cells during reparative regeneratrion after acute myocardial infarction

被引:37
作者
Karpov, RS [1 ]
Popov, SV [1 ]
Markov, VA [1 ]
Suslova, TE [1 ]
Ryabov, VV [1 ]
Poponina, YS [1 ]
Krylov, AL [1 ]
Sazonova, SV [1 ]
机构
[1] Russian Acad Med Sci, Siberian Div, Tomsk Res Ctr, Inst Cardiol, Tomsk, Russia
关键词
myocardial infarction; mononuclear bone marrow cells; cell cardiomyoplasty;
D O I
10.1007/s10517-006-0043-1
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
A randomized controlled study included 44 patients with acute myocardial infarction. It was found that intracoronary injection of bone marrow mononuclear cells is safe, ensures fixation of the injected cells in the myocardium, reduces blood levels of IL-1 beta and TNF-alpha, increases the content insulin-like growth factor, and does not provoke malignant arrhythmias.
引用
收藏
页码:640 / 643
页数:4
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