The predictive value of a 5-gene signature as a patient pre-selection tool in medulloblastoma for Hedgehog pathway inhibitor therapy

被引：5

作者：

Amakye, Dereck ^{[1
]}

Robinson, Douglas ^{[2
]}

Rose, Kristine ^{[1
]}

Cho, Jae ^{[3
]}

Ligon, Keith L. ^{[4
]}

Sharp, Thad ^{[1
]}

Haider, Asifa ^{[1
]}

Bandaru, Raj ^{[2
]}

Ando, Yuichi ^{[5
]}

Geoerger, Birgit ^{[6
]}

Doz, Francois ^{[7
,8
]}

Ashley, David ^{[9
]}

Hargrave, Darren ^{[10
]}

Casanova, Michela ^{[11
]}

Rodon, Jordi ^{[12
]}

Thomas, Anne ^{[13
]}

Mita, Alain ^{[14
]}

MacDonald, Tobey ^{[15
]}

Kieran, Mark W. ^{[4
]}

机构：

[1] Novartis Pharmaceut, E Hanover, NJ USA

[2] Novartis Inst BioMed Res, Cambridge, MA USA

[3] Stanford Sch Med, Palo Alto, CA USA

[4] Dana Farber Childrens Hosp, Ctr Canc, Boston, MA USA

[5] Nagoya Univ Hosp, Nagoya, Aichi, Japan

[6] Univ Paris Sud, Inst Gustave Roussy, Villejuif, France

[7] Inst Curie, Paris, France

[8] Univ Paris 05, Paris, France

[9] Deakin Univ, Barwon Hlth, Melbourne, Vic, Australia

[10] Great Ormond St Hosp Sick Children, London WC1N 3JH, England

[11] Ist Nazl Tumori, I-20133 Milan, Italy

[12] Vall dHebron Inst Oncol, Barcelona, Spain

[13] Univ Leicester, Leicester, Leics, England

[14] Canc Therapy & Res Ctr S Texas, San Antonio, TX 78229 USA

[15] Emory Childrens Ctr, Childrens Healthcare Atlanta, Atlanta, GA USA

来源：

CANCER RESEARCH | 2012年 / 72卷

关键词：

D O I：

10.1158/1538-7445.AM2011-4818

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

4818

引用

页数：2