Neurospora: a model of model microbes

被引：169

作者：

Davis, RH ^{[1
]}

Perkins, DD

机构：

[1] Univ Calif Irvine, Dept Mol Biol & Biochem, Irvine, CA 92697 USA

[2] Stanford Univ, Dept Biol Sci, Stanford, CA 94305 USA

来源：

NATURE REVIEWS GENETICS | 2002年 / 3卷 / 05期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

D O I：

10.1038/nrg797

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

In the 1940s, studies with Neurospora pioneered the use of microorganisms in genetic analysis and provided the foundations for biochemical genetics and molecular biology. What has happened since this orange mould was used to show that genes control metabolic reactions? How did it come to be the fungal counterpart of Drosophila? We describe its continued use during the heyday of research with Escherichia coli and yeast, and its emergence as a biological model for higher fungi.

引用

页码：397 / 403

页数：7

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