Multiple drug resistance

被引:1
作者
Mitscher, LA
Pillai, SP
Gentry, EJ
Shankel, DM
机构
[1] Univ Kansas, Dept Med Chem, Lawrence, KS 66045 USA
[2] Univ Kansas, Dept Mol Biosci, Lawrence, KS 66045 USA
关键词
multiple drug resistance;
D O I
10.1002/(SICI)1098-1128(199911)19:6<477::AID-MED2>3.3.CO;2-N
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Multiple drug resistance to antibacterial agents, antifungals, antivirals, antiprotozoals,and antitumor agents has risen spectacularly in the last decade or so and presently threatens eventually to put an end to successful chemotherapy in all of the above fields. This review summarizes the known origins of the problem, its present dimensions, the means employed to combat the phenomenon and promising avenues for future developments. (C) 1999 John Wiley & Sons, Inc.
引用
收藏
页码:477 / 496
页数:20
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