Synthesis of aromatic 1,2-diazines by inverse electron demand Diels-Alder reaction of polymer-supported 1,2,4,5-tetrazines

被引：61

作者：

Panek, JS

Zhu, B

机构：

[1] Department of Chemistry, Metcalf Ctr. for Sci. and Eng., Boston University, Boston

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 45期

关键词：

D O I：

10.1016/0040-4039(96)01866-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Inverse electron demand Diels-Alder reactions of unsymmetrically substituted 1,2,4,5-tetrazines immobilized on a solid support participate in thermally promoted cycloadditions with a wide range of electron-rich dienophiles. The reactions afford functionalized 1,2-diazines bearing a sulfur-based leaving group (-SR or -SO(2)R) at the C-6 position. Copyright (C) 1996 Elsevier Science Ltd

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页码：8151 / 8154

页数：4

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