Sibutramine in clinical practice

被引:7
作者
Finer, N [1 ]
机构
[1] Luton & Dunstable Hosp NHS Trust, Luton LU4 OD2, Beds, England
关键词
sibutramine; clinical issues; predicting response; initial weight loss;
D O I
10.1038/sj.ijo.0801932
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The role of sibutramine as an effective adjunct to diet and exercise in weight management programmes has been proven in clinical trials. Although the reality of managing obesity in clinical practice is very different from that of a controlled clinical trial, there is good evidence that sibutramine is an easy-to-use and highly effective additional therapy when used in everyday practice to manage obesity and its complications. It is possible to predict which patients will respond well to sibutramine treatment, and to modify programmes and support to ensure the best outcome for patients, whatever their clinical circumstances.
引用
收藏
页码:S12 / S15
页数:4
相关论文
共 6 条
[1]   Long-term maintenance of weight loss after a very-low-calorie diet: A randomized blinded trial of the efficacy and tolerability of sibutramine [J].
Apfelbaum, M ;
Vague, P ;
Ziegler, O ;
Hanotin, C ;
Thomas, F ;
Leutenegger, E .
AMERICAN JOURNAL OF MEDICINE, 1999, 106 (02) :179-184
[2]   Absence of cardiac valve dysfunction in obese patients treated with sibutramine [J].
Bach, DS ;
Rissanen, AM ;
Mendel, CM ;
Shepherd, G ;
Weinstein, SP ;
Kelly, F ;
Seaton, TB ;
Patel, B ;
Pekkarinen, TA ;
Armstrong, WF .
OBESITY RESEARCH, 1999, 7 (04) :363-369
[3]   Effect of sibutramine on weight maintenance after weight loss:: a randomised trial [J].
James, WPT ;
Astrup, A ;
Finer, N ;
Hilsted, J ;
Kopelman, P ;
Rössner, S ;
Saris, WHM ;
Van Gaal, LF .
LANCET, 2000, 356 (9248) :2119-2125
[4]  
MCNULTY S, 2000, INT J OBES RELAT S1, V24, pS320
[5]  
Scholze J., 2001, International Journal of Obesity, V25, pS106
[6]  
Smith IG, 2001, J FAM PRACTICE, V50, P505