5-bromo-2-iodopyrimidine: A novel, useful intermediate in selective palladium-catalysed cross-coupling reactions for efficient convergent syntheses

被引：25

作者：

Goodby, JW ^{[1
]}

Hird, M ^{[1
]}

Lewis, RA ^{[1
]}

Toyne, KJ ^{[1
]}

机构：

[1] UNIV HULL,KINGSTON HULL HU6 7RX,N HUMBERSIDE,ENGLAND

来源：

CHEMICAL COMMUNICATIONS | 1996年 / 24期

关键词：

D O I：

10.1039/cc9960002719

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple synthesis of the novel 5-bromo-2-iodopyrimidine is described and examples are provided of the use of the compound in selective palladium-catalysed cross-coupling reactions with a wide range of arylboronic acids and alkynylzincs to give the efficient syntheses of many substituted pyrimidine compounds.

引用

页码：2719 / 2720

页数：2

共 17 条

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