Medical need, scientific opportunity and the drive for antimalarial drugs

被引：652

作者：

Ridley, RG ^{[1
]}

机构：

[1] Med Malaria Venture, CH-1215 Geneva 15, Switzerland

来源：

NATURE | 2002年 / 415卷 / 6872期

关键词：

D O I：

10.1038/415686a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Continued and sustainable improvements in antimalarial medicines through focused research and development are essential for the world's future ability to treat and control malaria. Unfortunately, malaria is a disease of poverty, and despite a wealth of scientific knowledge there is insufficient market incentive to generate the competitive, business-driven industrial antimalarial drug research and development that is normally needed to deliver new products. Mechanisms of partnering with industry have been established to overcome this obstacle and to open up and build on scientific opportunities for improved chemotherapy in the future.

引用

页码：686 / 693

页数：8

共 99 条

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Alnwick D, 2000, B WORLD HEALTH ORGAN, V78, P1377

[2] Phenyl β-methoxyacrylates:: A new antimalarial pharmacophore [J].