Patients with congenital abnormality of platelet aggregation induced by Ca2+ ionophores may have a defect of the platelet P2Y12 receptor for ADP

被引：5

作者：

Cattaneo, M ^{[1
]}

Lecchi, A ^{[1
]}

机构：

[1] Univ Milan, IRCCS Osped Maggiore, Dept Internal Med, Aneglo Bianchi Bonomi Hemophilia & Thrombosis Ctr, I-20122 Milan, Italy

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 2001年 / 115卷 / 02期

关键词：

P2; receptors; P2Y12; ADP; disorders of platelet function; platelet aggregation;

D O I：

10.1046/j.1365-2141.2001.03115-3.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：485 / 486

页数：2

共 7 条

[1]

CATTANEO M, 1992, BLOOD, V80, P2787

[2] ADP receptors and clinical bleeding disorders [J].

Cattaneo, M ;

Gachet, C .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 1999, 19 (10) :2281-2285

[3] Platelets from a patient heterozygous for the defect of P2CYC receptors for ADP have a secretion defect despite normal thromboxane A2 production and normal granule stores -: Further evidence that some cases of platelet 'primary secretion defect' are heterozygous for a defect of P2CYC receptors [J].

Cattaneo, M ;

Lecchi, A ;

Lombardi, R ;

Gachet, C ;

Zighetti, ML .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2000, 20 (11) :E101-E106

[4] Pathogenetic analysis of three cases with a bleeding disorder characterized by defective platelet aggregation induced by Ca2+ ionophores [J].

Fuse, I ;

Higuchi, W ;

Uesugi, Y ;

Aizawa, Y .

BRITISH JOURNAL OF HAEMATOLOGY, 2001, 112 (03) :603-608

[5] PURINOCEPTORS ON BLOOD-PLATELETS - FURTHER PHARMACOLOGICAL AND CLINICAL-EVIDENCE TO SUGGEST THE PRESENCE OF 2 ADP RECEPTORS [J].

GACHET, C ;

CATTANEO, M ;

OHLMANN, P ;

HECHLER, B ;

LECCHI, A ;

CHEVALIER, J ;

CASSEL, D ;

MANNUCCI, PM ;

CAZENAVE, JP .

BRITISH JOURNAL OF HAEMATOLOGY, 1995, 91 (02) :434-444

[6] Identification of the platelet ADP receptor targeted by antithrombotic drugs [J].

Hollopeter, G ;

Jantzen, HM ;

Vincent, D ;

Li, G ;

England, L ;

Ramakrishnan, V ;

Yang, RB ;

Nurden, P ;

Nurden, A ;

Julius, D ;

Conley, PB .

NATURE, 2001, 409 (6817) :202-207

[7] AN INHERITED BLEEDING DISORDER LINKED TO A DEFECTIVE INTERACTION BETWEEN ADP AND ITS RECEPTOR ON PLATELETS - ITS INFLUENCE ON GLYCOPROTEIN IIB-IIIA COMPLEX FUNCTION [J].

NURDEN, P ;

SAVI, P ;

HEILMANN, E ;

BIHOUR, C ;

HERBERT, JM ;

MAFFRAND, JP ;

NURDEN, A .

JOURNAL OF CLINICAL INVESTIGATION, 1995, 95 (04) :1612-1622

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