β-Aminophosphonic compounds derived from methyl 1-dimethoxyphosphoryl-2-succinimidocyclohex-3-ene-1-carboxylates

被引：11

作者：

Defacqz, N

Touillaux, R

Cordi, A

Marchand-Byrnaert, J

机构：

[1] Univ Catholique Louvain, Dept Chim, Unite Chim Organ & Med, B-1348 Louvain, Belgium

[2] Univ Catholique Louvain, Dept Chim, Unite Chim Struct & Mecanismes Reactionnels, B-1348 Louvain, Belgium

[3] Inst Rech Servier, F-92150 Suresnes, France

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2001年 / 20期

关键词：

D O I：

10.1039/b105111n

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Compounds 3a,b, the [4 + 2] cycloadducts of trimethyl 2-phosphonoacrylate and N-buta-1,3-dienylsuccinimide, have been transformed into various beta -aminophosphonic acid derivatives 4-17 by selective deprotection, epoxidation, dihydroxylation, and oxidative cleavage of the cyclohexenyl C-C double bond.

引用

页码：2632 / 2637

页数：6

共 34 条

[1] Regulation of protein phosphatase-1 [J].