Geraniol is a potent inducer of apoptosis-like cell death in the cultured shoot primordia of Matricaria chamomilla

被引：32

作者：

Izumi, S ^{[1
]}

Takashima, O ^{[1
]}

Hirata, T ^{[1
]}

机构：

[1] Hiroshima Univ, Grad Sch Sci, Dept Math & Life Sci, Higashihiroshima 7398526, Japan

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1999年 / 259卷 / 03期

关键词：

D O I：

10.1006/bbrc.1999.0813

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We screened various isoprenoids to search for inducers of apoptosis-like cell death ("apoptosis") in the shoot primordia of Matricaria chamomilla and found that geraniol has the most potent apoptosis-inducing activity among terpenoids, as judged from DNA fragmentation in the cells. The apoptosis-inducing activity of geraniol is concentration and time dependent. Morphologically, the nuclei of the cells treated with 5 mM geraniol were condensed and fragmented. (C) 1999 Academic Press.

引用

页码：519 / 522

页数：4

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