Enantioselective accumulation of (-)-pinoresinol through O-demethylation of (+/-)-eudesmin by Aspergillus niger

被引：10

作者：

Kasahara, H ^{[1
]}

Miyazawa, M ^{[1
]}

Kameoka, H ^{[1
]}

机构：

[1] KINKI UNIV,FAC SCI & ENGN,DEPT APPL CHEM,HIGASHIOSAKA,OSAKA 577,JAPAN

来源：

PHYTOCHEMISTRY | 1997年 / 44卷 / 08期

关键词：

Aspergillus niger; fungus; (+/-)-eudesumin; (-)-pinoresinol; O-demthylation; enantioselective accumulation;

D O I：

10.1016/S0031-9422(96)00754-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Microbial transformation of (+/-)-eudesmin by Aspergillus niger was investigated. Enantioselective accumulation of (-)-pinoresinol was shown through O-demethylation of (+/-)-eudesmin. This fungus O-demethylated both enantiomers of eudesmin, but the conversion rates for each enantiomer were clearly different. Copyright (C) 1997 Elsevier Science Ltd.

引用

页码：1479 / 1482

页数：4

共 14 条

[1]

AYRES DC, 1990, LIGNANS CHEM BIOL CL

[2]

DEYAMA T, 1983, CHEM PHARM BULL, V31, P2993

[3]

GOTTLIEB OR, 1989, NATURAL PRODUCTS WOO, V1, P441

[4] HYDROPEROXYSESQUITERPENE AND LIGNAN CONSTITUENTS OF MAGNOLIA-KOBUS [J].

IIDA, T ;

NAKANO, M ;

ITO, K .

PHYTOCHEMISTRY, 1982, 21 (03) :673-675

[5] STUDIES ON THE CHEMICAL-CONSTITUENTS OF RUTACEOUS PLANTS .48. THE CHEMICAL-CONSTITUENTS OF XANTHOXYLUM-AILANTHOIDES SIEB ET ZUCC [FAGARA-AILANTHOIDES (SIEB ET ZUCC) ENGL.] .3. ISOLATION OF THE CHEMICAL-CONSTITUENTS OF THE BARK [J].

ISHII, H ;

ISHIKAWA, T ;

MIHARA, M ;

AKAIKE, M .

YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1983, 103 (03) :279-292

[6] LIGNANS IN FLOWER BUDS OF MAGNOLIA-FARGESII [J].

KAKISAWA, H ;

CHEN, YP ;

HSU, HY .

PHYTOCHEMISTRY, 1972, 11 (07) :2289-&

[7]

KASAHARA H, 1996, PHYTOCHEMISTRY, V39, P1027

[8]

KATAYAMA T, 1991, PHYTOCHEMISTRY, V31, P3875

[9] BIOLOGICAL-ACTIVITIES OF LIGNANS [J].

MACRAE, WD ;

TOWERS, GHN .

PHYTOCHEMISTRY, 1984, 23 (06) :1207-1220

[10] BIOTRANSFORMATION OF LIGNANS - A SPECIFIC MICROBIAL OXIDATION OF (+)-EUDESMIN AND (+)-MAGNOLIN BY ASPERGILLUS-NIGER [J].

MIYAZAWA, M ;

KASAHARA, H ;

KAMEOKA, H .

PHYTOCHEMISTRY, 1993, 34 (06) :1501-1507

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