GLP-1 and cerebral detection of glucose, a key mechanism for the regulation of glucose homeostasis

被引:2
作者
Burcelin, R [1 ]
Cani, PD [1 ]
Knauf, C [1 ]
机构
[1] Univ Toulouse 3, IFR31, CNRS, UMR 5018,CHU Rangueil, F-31432 Toulouse 4, France
来源
M S-MEDECINE SCIENCES | 2006年 / 22卷 / 03期
关键词
D O I
10.1051/medsci/2006223237
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
引用
收藏
页码:237 / 239
页数:3
相关论文
共 10 条
[1]   Portal glucose infusion in the mouse induces hypoglycemia - Evidence that the hepatoportal glucose sensor stimulates glucose utilization [J].
Burcelin, R ;
Dolci, W ;
Thorens, B .
DIABETES, 2000, 49 (10) :1635-1642
[2]   Glucose sensing by the hepatoportal sensor is GLUT2-dependent - In vivo analysis in GLUT2-null mice [J].
Burcelin, R ;
Dolci, W ;
Thorens, B .
DIABETES, 2000, 49 (10) :1643-1648
[3]   GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor-stimulated muscle glucose utilization [J].
Burcelin, R ;
Crivelli, V ;
Perrin, C ;
Da Costa, A ;
Mu, J ;
Kahn, BB ;
Birnbaum, MJ ;
Kahn, CR ;
Vollenweider, P ;
Thorens, B .
JOURNAL OF CLINICAL INVESTIGATION, 2003, 111 (10) :1555-1562
[4]   Glucagon-like peptides [J].
Drucker, DJ .
DIABETES, 1998, 47 (02) :159-169
[5]   Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans [J].
Holst, JJ ;
Gromada, J .
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2004, 287 (02) :E199-E206
[6]   Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage [J].
Knauf, C ;
Cani, PD ;
Perrin, C ;
Iglesias, MA ;
Maury, JF ;
Bernard, E ;
Benhamed, F ;
Grémeaux, T ;
Drucker, DJ ;
Kahn, CR ;
Girard, J ;
Tanti, JF ;
Delzenne, NM ;
Postic, C ;
Burcelin, R .
JOURNAL OF CLINICAL INVESTIGATION, 2005, 115 (12) :3554-3563
[7]   Regulation of glucagon secretion by glucose transporter type 2 (glut2) and astrocytedependent glucose sensors [J].
Marty, N ;
Dallaporta, M ;
Foretz, M ;
Emery, M ;
Tarussio, D ;
Bady, I ;
Binnert, C ;
Beermann, F ;
Thorens, B .
JOURNAL OF CLINICAL INVESTIGATION, 2005, 115 (12) :3545-3553
[8]   How astrocytes feed hungry neurons [J].
Pellerin, L .
MOLECULAR NEUROBIOLOGY, 2005, 32 (01) :59-72
[9]   PLASMA INSULIN RESPONSES TO ORAL AND INTRAVENOUS GLUCOSE - STUDIES IN NORMAL AND DIABETIC SUBJECTS [J].
PERLEY, MJ ;
KIPNIS, DM .
JOURNAL OF CLINICAL INVESTIGATION, 1967, 46 (12) :1954-&
[10]   Long-term modulation of glucose utilization by IL-1α and TNF-α in astrocytes:: Na+ pump activity as a potential target via distinct signaling mechanisms [J].
Véga, C ;
Pellerin, L ;
Dantzer, R ;
Magistretti, PJ .
GLIA, 2002, 39 (01) :10-18