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Molecular pathogenesis of Bacillus anthracis infection

被引：112
作者：
Little, SF [1 ]
Ivins, BE [1 ]
机构：
[1] USA, Med Res Inst Infect Dis, Frederick, MD 21702 USA
来源：
MICROBES AND INFECTION | 1999年 / 1卷 / 02期
关键词：
Bacillus anthracis; anthrax; pathogenesis; vaccine;
D O I：
10.1016/S1286-4579(99)80004-5
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
This review summarizes the current knowledge pertaining to the pathogenesis of infection with Bacillus anthracis relative to the two exotoxins and the capsule. Emphasis is given to the structure and activities of the individual components of the exotoxins, their interaction with cells, and the response of macrophages to lethal toxin. Finally, results from vaccination studies are reviewed. (C) Elsevier, Paris.
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页码：131 / 139
页数：9
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