Synthesis of (+)-8-deoxyvernolepin

被引：11

作者：

Astudillo, L

Gonzalez, AG

Galindo, A

Mansilla, H

机构：

[1] UNIV LA LAGUNA,INST UNIV BIOORGAN,LA LAGUNA 38206,TENERIFE,SPAIN

[2] CSIC,INST PROD NAT & AGROBIOL,LA LAGUNA 38206,TENERIFE,SPAIN

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 38期

关键词：

D O I：

10.1016/S0040-4039(97)01540-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of (+)-8-deoxyvernolepin 1b was accomplished by a short and efficient route from arsantin 5. The key step involves a drastic rearrangement of an iodomesylate intermediate 4a by the action of zinc. (C) 1997 Elsevier Science Ltd.

引用

页码：6737 / 6740

页数：4

共 15 条

[1] SYNTHESIS OF TERPENOID COMPOUNDS FROM ALPHA-SANTONIN
BANERJEE, AK
VERA, WJ
GONZALEZ, NC
[J]. TETRAHEDRON, 1993, 49 (22) : 4761 - 4788
[2] SYNTHESIS OF A CYTOTOXIC VERNOLEPIN PROTOTYPE - OZONIZATION OF SILYLOXYALKENES
CLARK, RD
HEATHCOCK, CH
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1976, 41 (08) : 1396 - 1403
[3] STEROIDAL N-NITROAMINES .4. INTRAMOLECULAR FUNCTIONALIZATION OF N-NITROAMINE RADICALS - SYNTHESIS OF 1,4-NITROIMINE COMPOUNDS
DEARMAS, P
FRANCISCO, CG
HERNANDEZ, R
SALAZAR, JA
SUAREZ, E
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1988, (12): : 3255 - 3265
[4] FLORENT JC, 1987, J AMC HEM SOC, V52, P1052
[5] FUJIMOTO Y, 1979, CHEM PHARM BULL, V27, P923
[6] FUJIMOTO Y, 1980, TETRAHEDRON LETT, V28, P3409
[7] A DIRECT SYNTHESIS OF CYCLIC ACETALS FROM BETA-HYDROXY OR GAMMA-HYDROXY ETHERS BY MEANS OF C-H ACTIVATION
FURUTA, K
NAGATA, T
YAMAMOTO, H
[J]. TETRAHEDRON LETTERS, 1988, 29 (18) : 2215 - 2218
[8] GRIECO PA, 1977, J ORG CHEM, V20, P495
[9] SYNTHESIS OF (+)-8-DEOXYVERNOLEPIN
HERNANDEZ, R
VELAZQUEZ, SM
SUAREZ, E
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (21) : 6395 - 6403
[10] TUMOR INHIBITORS .69. STRUCTURE-CYTOTOXICITY RELATIONSHIPS AMONG SESQUITERPENE LACTONES
KUPCHAN, SM
EAKIN, MA
THOMAS, AM
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1971, 14 (12) : 1147 - &

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