Bacterial genomics: the use of DNA microarrays and bacterial artificial chromosomes

被引：11

作者：

Ball, KD ^{[1
]}

Trevors, JT ^{[1
]}

机构：

[1] Univ Guelph, Dept Environm Biol, Guelph, ON N1G 2W1, Canada

来源：

JOURNAL OF MICROBIOLOGICAL METHODS | 2002年 / 49卷 / 03期

基金：

加拿大自然科学与工程研究理事会;

关键词：

bacteria bacterial artificial chromosome (BAC); genomics; microarrays; expression; microorganism;

D O I：

10.1016/S0167-7012(01)00375-X

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Immense amounts of genetic information are contained within microbial genomes. As the number of completely sequenced microbial genornes is increasing, functional and comparative genomic techniques will be employed for sequence analysis and gene characterization. Sequence comparison and expression profiling by DNA microarrays can determine phylogenetic relationships and identify genes while bacterial artificial chromosomes (BACs) allow the study of entire biochemical pathways and permit the expression of bacterial genes in a foreign host. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：275 / 284

页数：10

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