Predictive value of nalidixic acid resistance for detecting salmonellae with decreased ciprofloxacin susceptibility

被引：13

作者：

Albayrak, F

Cokca, F

Erdem, B

Aysev, AD

机构：

[1] Ankara Univ, Fac Med, Clin Bacteriol & Infect Dis Dept, TR-06450 Ankara, Turkey

[2] Ankara Univ, Fac Med, Microbiol & Clin Microbiol Dept, TR-06450 Ankara, Turkey

[3] Ankara Univ, Fac Med, Pediat Infect Dis Dept, TR-06450 Ankara, Turkey

来源：

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | 2004年 / 23卷 / 04期

关键词：

nalidixic acid resistance; ciprofloxacin susceptibility; salmonellae;

D O I：

10.1016/j.ijantimicag.2003.09.014

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Seventy-three Salmonella isolates classified as ciprofloxacin susceptible when using the criteria of the National Committee for Clinical Laboratory Standards were studied for nalidixic acid (NA) resistance. The aim of the study was to determine the predictive value of nalidixic, acid resistance in screening for decreased ciprofloxacin susceptibility. We observed that isolates with decreased ciprofloxacin Susceptibility were all resistant to nalidixic acid. Identification of nalidixic acid resistance by the disk diffusion method provided 100% sensitivity and a specificity of 98.4% in strains with minimum inhibitory concentrations (MICs) >0.008 mg/l. (C) 2004 Published by Elsevier B.V. and the International Society of Chemotherapy.

引用

页码：332 / 336

页数：5

共 29 条

[1] Is it time to change fluoroquinolone breakpoints for Salmonella spp.? [J].