Iodine/MeOH: a novel and efficient reagent system for thiocyanation of aromatics and heteroaromatics

被引：141

作者：

Yadav, JS ^{[1
]}

Reddy, BVS ^{[1
]}

Shubashree, S ^{[1
]}

Sadashiv, K ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 14期

关键词：

thiocyanation; aromatic systems; iodine catalysis; aryl thiocyanates;

D O I：

10.1016/j.tetlet.2004.02.073

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Indoles, pyrroles, oxindoles and aromatic amino compounds undergo smooth thiocyanation with ammonium thiocyanate in the presence of molecular iodine in methanol under mild conditions to afford the corresponding 3-indolyl, 2-pyrrolyl and 4-aryl thiocyanates, respectively, in excellent yields with high selectivity. The reactions proceed rapidly at room temperature without heating or the use of strong Lewis acids. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：2951 / 2954

页数：4

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