The essential oil constituents and antimicrobial activity of Anthemis aciphylla Boiss. var. discoidea Boiss.

被引:46
作者
Baser, KHC
Demirci, B
Iscan, G
Hashimoto, T
Demirci, F
Noma, Y
Asakawa, Y
机构
[1] Tokushima Bunri Univ, Fac Pharmaceut Sci, Tokushima 7708055, Japan
[2] Tokushima Bunri Univ, Fac Domest Sci, Tokushima 7708055, Japan
[3] Anadolu Univ, Fac Pharm, Dept Pharmacognosy, TR-26470 Eskisehir, Turkey
关键词
Anthemis aciphylla var. discoidea; Asteraceae; essential oil; isofaurinone; antimicrobial activity;
D O I
10.1248/cpb.54.222
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The essential oil of aerial parts, leaves and flowers of the endemic Anthemis aciphylla BOISS. var. discoidea BOISS. (Asteraceae) were obtained by hydrodistillation. The oils were analyzed both by GC and GC-MS on a polar column. The monoterpenes alpha-pinene (9-49%) and terpinen-4-ol (22-32%) were characterized as the main constituents. An unknown component isolated from the essential oil was characterized by means of MS, HR-MS, FT-IR, 1D- and 2D-NMR techniques as isofaurinone (1). Furthermore, the biological activity of the essential oils was evaluated in various human pathogenic microorganisms using the broth microdilution method. Weak to moderate inhibitions (0.06-1.0 mg/ml) was observed.
引用
收藏
页码:222 / 225
页数:4
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