A Novel, One-Pot, Efficient Synthesis of 2-Aroyl-1,4-diaryl-7,9-dimethyl-7,9-diazaspiro[4.5]deca-1,3-diene-6,8,10-triones

被引：21

作者：

Adib, Mehdi ^{[1
]}

Sayahi, Mohammad Hosein ^{[1
]}

Ziyadi, Hakimeh ^{[1
]}

Zhu, Long-Guan ^{[2
]}

Bijanzadeh, Hamid Reza ^{[3
]}

机构：

[1] Univ Tehran, Univ Coll Sci, Sch Chem, Tehran, Iran

[2] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China

[3] Tarbiat Modares Univ, Dept Chem, Tehran, Iran

来源：

SYNTHESIS-STUTTGART | 2008年 / 20卷 / 20期

关键词：

spiro compounds; cyclopentadienes; cyclizations; aldehydes; alkynes; heterocycles;

D O I：

10.1055/s-0028-1083157

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel and efficient synthesis of 2-aroyl-1,4-diaryl-7,9-dimethyl-7,9-diazaspiro[4.5]deca-1,3-diene-6,8,10-triones is described. The reactive 1:1 zwitterionic intermediate, formed by the addition of triphenylphosphine to diaroylacetylenes, was trapped by a Knoevenagel condensation product prepared in situ by reaction of N,N-dimethylbarbituric acid and aromatic aldehydes, to afford the title compounds in excellent yields under mild reaction conditions.

引用

页码：3289 / 3294

页数：6

共 54 条

[1] Novel NLO-phores with proaromatic donor and acceptor groups [J].