Synthesis of cyclic dienamide using ruthenium-catalyzed ring-closing metathesis of ene-ynamide

被引：130

作者：

Saito, N ^{[1
]}

Sato, Y ^{[1
]}

Mori, M ^{[1
]}

机构：

[1] Hokkaido Univ, Grad Sch Pharmaceut Sci, Sapporo, Hokkaido 0600812, Japan

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 05期

关键词：

D O I：

10.1021/ol017298y

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Ring-closing metathesis of ene-ynamide using the second-gene ration Grubbs' catalyst produced nitrogen-containing heterocycles, which have dienamide moieties, in high yields. Diels-Alder reaction of the cyclized product and dienophile proceeded smoothly to afford a bi- or tricyclic compound.

引用

页码：803 / 805

页数：3

共 55 条

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