Infectious particles derived from Semliki Forest virus vectors encoding murine leukemia virus envelopes

被引：19

作者：

Lebedeva, I ^{[1
]}

Fujita, K ^{[1
]}

Nihrane, A ^{[1
]}

Silver, J ^{[1
]}

机构：

[1] NIAID,MOL MICROBIOL LAB,NATL INST HLTH,BETHESDA,MD 20892

来源：

JOURNAL OF VIROLOGY | 1997年 / 71卷 / 09期

关键词：

D O I：

10.1128/JVI.71.9.7061-7067.1997

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Semliki Forest virus vectors encoding murine leukemia virus (MLV) envelope protein with a truncated cytoplasmic tail generate submicrometer, cell-associated, membranous particles that transmit replication competent vector RNA specifically to cells bearing the MLV receptor. Such ''minimal'' viruses could have applications as retroviral vaccines or in the study of virus evolution.

引用

页码：7061 / 7067

页数：7

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