Structure and function of bacterial initiation factors

被引：59

作者：

Boelens, R

Gualerzi, CO

机构：

[1] Univ Utrecht, Bijvoet Ctr Biomol Res, NL-3584 CH Utrecht, Netherlands

[2] Univ Camerino, Dept Biol, Genet Lab, I-62032 Camerino, MC, Italy

来源：

CURRENT PROTEIN & PEPTIDE SCIENCE | 2002年 / 3卷 / 01期

关键词：

D O I：

10.2174/1389203023380765

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Bacteria require three initiation factors, IF1, IF2 and IF3, to start protein synthesis. In the last few years the elucidation of both structural and mechanistic aspects pertaining to these proteins has made substantial progress. In this article we outline the translation initiation process in bacteria and review these recent developments giving a summary of the main features of the structure and function of the initiation factors.

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页码：107 / 119

页数：13

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