Zerumbone, an HIV-inhibitory and cytotoxic sesquiterpene of Zingiber aromaticum and Z-zerumbet

被引：60

作者：

Dai, JR ^{[1
]}

Cardellina, JH ^{[1
]}

McMahon, JB ^{[1
]}

Boyd, MR ^{[1
]}

机构：

[1] NCI,LAB DRUG DISCOVERY RES & DEV,DEV THERAPEUT PROGRAM,DIV CANC TREATMENT DIAGNOSIS & CTR,FREDERICK,MD 21702

来源：

NATURAL PRODUCT LETTERS | 1997年 / 10卷 / 02期

关键词：

HIV-inhibitory; sesquiterpene; zerumbone; Zingiber;

D O I：

10.1080/10575639708043725

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Zerumbone and 3 '',4 ''-O-diacetylafzelin were isolated from organic extracts of rhizomes of Zingiber aromaticum (Zingiberaceae), and zerumbone and 4 ''-O-acetylafzelin were obtained from organic extracts of entire plants of Z. zerumbet. Zerumbone exhibited HIV-inhibitory and cytotoxic activities, while the afzelins were inactive in both assays.

引用

页码：115 / 118

页数：4

共 9 条

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