Acute lung injury in acute pancreatitis - Awaiting the big leap

被引：66

作者：

Akbarshahi, Hamid ^{[1
]}

Rosendahl, Ann H. ^{[1
]}

Westergren-Thorsson, Gunilla ^{[2
]}

Andersson, Roland ^{[1
]}

机构：

[1] Skane Univ Hosp Lund, Dept Surg, Lund, Sweden

[2] Lund Univ, Unit Lung Biol, Div Vasc & Resp Res, Dept Expt Med Sci, S-22100 Lund, Sweden

来源：

RESPIRATORY MEDICINE | 2012年 / 106卷 / 09期

关键词：

Acute lung injury; Acute pancreatitis; Pathophysiological mechanisms; Intervention; PLATELET-ACTIVATING-FACTOR; RESPIRATORY-DISTRESS-SYNDROME; TUMOR-NECROSIS-FACTOR; CERULEIN-INDUCED PANCREATITIS; ACUTE NECROTIZING PANCREATITIS; NF-KAPPA-B; NEUTROPHIL CHEMOATTRACTANT PRODUCTION; KUPFFER CELL ACTIVATION; PERITONEAL-MACROPHAGES; ALVEOLAR MACROPHAGES;

D O I：

10.1016/j.rmed.2012.06.003

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Acute lung injury is a severe complication to acute pancreatitis and a significant health problem associated with a considerable mortality. Underlying mechanisms are complex and poorly understood, although recent insights have identified several inflammatory profiles and cellular components involved to varying degrees during different phases of pancreatitis exacerbation and acute lung injury. This review aims to highlight the current understanding of the inflammatory and cellular components involved in and responsible for the associations of acute pancreatitis and acute lung injury, with the hope of thereby providing an increased understanding of the underlying mechanisms. In addition, novel experimental models of modulating the pancreatitis-associated acute lung injury are presented, interventions that may be of potential future clinical value. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：1199 / 1210

页数：12

共 147 条

[1]

Tissue-specific regulation of glutamine synthetase gene expression in acute pancreatitis is confirmed by using interleukin-1 receptor knockout mice [J].

Abcouwer, SF ;

Norman, J ;

Fink, G ;

Carter, G ;

Lustig, RJ ;

Souba, WW .

SURGERY, 1996, 120 (02) :255-264

[2]

Fatal Acute Pancreatitis Occurring Outside of the Hospital: Clinical and Social Characteristics [J].

Andersson, Bodil ;

Ansari, Daniel ;

Andersson, Ellen ;

Persson, Sixten ;

Andersson, Roland .

WORLD JOURNAL OF SURGERY, 2010, 34 (10) :2286-2291

[3]

Incidence, management and recurrence rate of acute pancreatitis [J].

Andersson, R ;

Andersson, B ;

Haraldsen, P ;

Drewsen, G ;

Eckerwall, G .

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 2004, 39 (09) :891-894

[4]

Averill S, 2002, J NEUROSCI, V22, P7493

[5]

A DOUBLE-BLIND STUDY OF TRASYLOL IN TREATMENT OF PANCREATITIS [J].

BACHRACH, WH ;

SCHILD, PD .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1968, 146 (A2) :580-+

[6]

REPORT OF THE AMERICAN-EUROPEAN CONSENSUS CONFERENCE ON ARDS - DEFINITIONS, MECHANISMS, RELEVANT OUTCOMES AND CLINICAL-TRIAL COORDINATION [J].

BERNARD, GR ;

ARTIGAS, A ;

BRIGHAM, KL ;

CARLET, J ;

FALKE, K ;

HUDSON, L ;

LAMY, M ;

LEGALL, JR ;

MORRIS, A ;

SPRAGG, R ;

DHAINAUT, JF ;

MATTHAY, M ;

MANCEBO, J ;

MEYRICK, B ;

PAYEN, D ;

PERRET, C ;

FOWLER, AA ;

SCHALLER, MD ;

VANASBECK, BS ;

COCHIN, B ;

LANKEN, PN ;

LEEPER, KV ;

MARINI, J ;

MURRAY, JF ;

OPPENHEIMER, L ;

PESENTI, A ;

REID, L ;

RINALDO, J ;

VILLAR, J ;

Hyers, T ;

Knaus, W ;

Matthay, R ;

Pinsky, M ;

Bone, RC ;

Bosken, C ;

Johanson, WG ;

Lewandowski, K ;

Repine, J ;

Rodriguez-Roisin, R ;

Roussos, C .

INTENSIVE CARE MEDICINE, 1994, 20 (03) :225-232

[7]

Bhatia M, 2000, J PATHOL, V190, P117

[8]

Role of hydrogen sulfide in acute pancreatitis and associated lung injury [J].

Bhatia, M ;

Wong, FL ;

Fu, D ;

Lau, HY ;

Moochhala, SM ;

Moore, PK .

FASEB JOURNAL, 2005, 19 (01) :623-+

[9]

Role of substance P and the neurokinin 1 receptor in acute pancreatitis and pancreatitis-associated lung injury [J].

Bhatia, M ;

Saluja, AK ;

Hofbauer, B ;

Frossard, JL ;

Lee, HS ;

Castagliuolo, I ;

Wang, CC ;

Gerard, N ;

Pothoulakis, C ;

Steer, ML .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (08) :4760-4765

[10]

Preprotachykinin-A gene deletion protects mice against acute pancreatitis and associated lung injury [J].

Bhatia, M ;

Slavin, J ;

Cao, YQ ;

Basbaum, AI ;

Neoptolemos, JP .

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2003, 284 (05) :G830-G836

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