Total synthesis of the cholesterol biosynthesis inhibitor 1233A via a (π-allyl)tricarbonyliron lactone complex

被引：17

作者：

Bates, RW

Fernández-Megía, E

Ley, SV

Rück-Braun, K

Tilbrook, DMG

机构：

[1] Univ Cambridge, Chem Lab, Cambridge CB2 1EW, England

[2] Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1999年 / 14期

关键词：

D O I：

10.1039/a903641e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The total synthesis of the P-lactone cholesterol synthase inhibitor 1233A (1) is described employing the oxidative decomplexation of a (pi-allyl)tricarbonyliron lactone (2) as the key synthetic step.

引用

页码：1917 / 1925

页数：9

共 37 条

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