A comparison of iron absorption from single meals and daily diets using radioFe (Fe-55,Fe-59)

The purpose of the present study was to compare two measures of Fe absorption, one from single meals and the other from daily diets, Ten ileostomy subjects were given the same low-fibre composite diet for all three meals each day for five consecutive days. After 3 weeks the experiment was repeated with a high-fibre diet. The morning meal constituted one-seventh of the total daily diet intake, the mid-day meal two-sevenths and the evening meal four-sevenths of the total daily diet intake, On days 4 and 5 of each diet period the morning meal was labelled with Fe-55 and all three meals were labelled with Fe-59, The activities retained in the subjects 19 d later showed the Fe absorption from the low-fibre diet measured from the morning meals to be almost 80 % greater than the average Fe absorption measured from all meals during the same 2 d. With the high-fibre diet the absorption from the morning meals was less than 50 % greater than the average for all meals but the difference was not significant, We suggest that all meals of the day should be labelled with radioFe in order to avoid inflating the measures of Fe absorption.