Interaction of hydroxy acids with β-cyclodextrin

被引：43

作者：

Fenyvesi, E

Vikmon, M

Szeman, J

Redenti, E

Delcanale, M

Ventura, P

Szejtli, J

机构：

[1] Cyclolab Res & Dev Lab Ltd, H-1117 Budapest, Hungary

[2] Chiesi Farmaceut SPA, Parma, Italy

来源：

JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY | 1999年 / 33卷 / 03期

关键词：

beta-cyclodextrin; citric acid; tartaric acid; malic acid; hydroxy acids; solubility;

D O I：

10.1023/A:1008094702632

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The solubility of beta-cyclodextrin (beta-CD) was studied in aqueous solutions of various organic acids. The hydroxy acids, especially citric and tartaric acid were found to increase the solubility of beta-CD, while some other carboxylic acids reduced it. From solubility data the apparent complex association constants were calculated.

引用

页码：339 / 344

页数：6

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