Cholesterol: stuck in traffic

被引：28

作者：

Mukherjee, S ^{[1
]}

Maxfield, FR ^{[1
]}

机构：

[1] Cornell Univ, Weill Med Coll, Dept Biochem, New York, NY 10021 USA

来源：

NATURE CELL BIOLOGY | 1999年 / 1卷 / 02期

关键词：

D O I：

10.1038/10030

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Niemann-Pick type C is a genetic disorder thought to be partly characterized by a defect in cholesterol storage in lysosomes. New findings show that in fact cholesterol accumulates in late endosomes, and this accumulation leads to the redistribution of membrane proteins.

引用

页码：E37 / E38

页数：2

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