Stereoselective syntheses of cytoxazone, a novel cytokine modulator, and its stereoisomers

被引：57

作者：

Sakamoto, Y ^{[1
]}

Shiraishi, A ^{[1
]}

Seonhee, J ^{[1
]}

Nakata, T ^{[1
]}

机构：

[1] Inst Phys & Chem Res RIKEN, Wako, Saitama 3510198, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 22期

关键词：

oxazolidinones; stereocontrol; azides; sharpless asymmetric dihydroxylation;

D O I：

10.1016/S0040-4039(99)00712-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cytoxazone, a novel cytokine modulator, and its stereoisomers were stereoselectively synthesized via stereocontrolled introduction of an azide group and direct construction of the 2-oxazolidinone ring from an azide carbonate by reductive cyclization. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：4203 / 4206

页数：4

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