International consensus on (ICON) pediatric asthma

被引:398
作者
Papadopoulos, N. G. [1 ]
Arakawa, H. [2 ]
Carlsen, K. -H. [3 ]
Custovic, A. [4 ]
Gern, J. [5 ]
Lemanske, R. [6 ]
Le Souef, P. [7 ]
Makela, M. [8 ]
Roberts, G. [9 ]
Wong, G. [10 ]
Zar, H. [11 ]
Akdis, C. A. [12 ]
Bacharier, L. B. [13 ,15 ]
Baraldi, E. [14 ]
van Bever, H. P. [16 ]
de Blic, J. [17 ]
Boner, A. [18 ]
Burks, W. [19 ]
Casale, T. B. [20 ]
Castro-Rodriguez, J. A. [21 ]
Chen, Y. Z. [23 ]
El-Gamal, Y. M. [22 ]
Everard, M. L. [24 ]
Frischer, T. [26 ]
Geller, M. [25 ]
Gereda, J. [27 ]
Goh, D. Y. [28 ]
Guilbert, T. W.
Hedlin, G. [29 ]
Heymann, P. W. [30 ]
Hong, S. J. [31 ]
Hossny, E. M. [32 ]
Huang, J. L. [33 ]
Jackson, D. J. [34 ]
de Jongste, J. C. [35 ]
Kalayci, O. [36 ]
Ait-Khaled, N. [37 ]
Kling, S. [38 ]
Kuna, P. [39 ]
Lau, S. [40 ]
Ledford, D. K. [41 ]
Lee, S. I. [42 ]
Liu, A. H. [43 ]
Lockey, R. F. [41 ]
Lodrup-Carlsen, K. [45 ]
Lotvall, J. [47 ]
Morikawa, A. [46 ]
Nieto, A. [48 ]
Paramesh, H. [49 ]
Pawankar, R. [50 ]
机构
[1] Univ Athens, Dept Allergy, Pediat Clin 2, Athens 11527, Greece
[2] Gunma Univ, Grad Sch Med, Dept Pediat, Gunma, Japan
[3] Oslo Univ Hosp, Dept Pediat, Oslo, Norway
[4] Univ Hosp S Manchester NHS Fdn Trust, Resp Res Grp, Manchester, Lancs, England
[5] Univ Wisconsin, Sch Med, Dept Pediat, Madison, WI USA
[6] Univ Wisconsin, Sch Med & Publ Hlth, Div Pediat Allergy Immunol & Rheumatol, Madison, WI USA
[7] Univ Western Australia, Princess Margaret Hosp, Sch Pediat & Child Hlth, Perth, WA 6009, Australia
[8] Univ Helsinki, Cent Hosp, Pediat Unit, Helsinki, Finland
[9] Southampton Univ Hosp NHS Trust, Acad Unit Human Dev & Hlth, Southampton, Hants, England
[10] Chinese Univ Hong Kong, Dept Pediat, Sha Tin, Hong Kong, Peoples R China
[11] Univ Cape Town, Red Cross War Mem Childrens Hosp, Dept Pediat & Child Hlth, ZA-7925 Cape Town, South Africa
[12] Swiss Inst Allergy & Asthma Res SIAF, Davos, Switzerland
[13] Washington Univ, Sch Med, Dept Pediat, Div Pediat Allergy Immunol & Pulm Med, St Louis, MO 63110 USA
[14] Univ Padua, Dept Pediat, Unit Allergy & Resp Med, Padua, Italy
[15] St Louis Childrens Hosp, St Louis, MO 63178 USA
[16] Natl Univ Hlth Syst, Natl Univ Hosp, Childrens Med Inst, Dept Paediat, Singapore, Singapore
[17] Univ Paris 05, AP HP, Serv Pneumol & Allergol Pediat, Paris, France
[18] Univ Verona, Dept Paediat, I-37100 Verona, Italy
[19] Duke Univ, Med Ctr, Dept Pediat, Div Allergy & Immunol, Durham, NC 27710 USA
[20] Creighton Univ, Div Allergy & Immunol, Dept Med, Omaha, NE 68178 USA
[21] Pontificia Univ Catolica Chile, Sch Med, Santiago, Chile
[22] Ain Shams Univ, Pediat Allergy & Immunol Unit, Cairo, Egypt
[23] Capital Inst Pediat, Beijing, Peoples R China
[24] Sheffield Childrens Hosp, Dept Resp Med, Sheffield, S Yorkshire, England
[25] Geller Allergy & Immunol Clin, Rio De Janeiro, Brazil
[26] Univ Childrens Hosp Vienna, Vienna, Austria
[27] Clin Ricardo Palma, Dept Allergy & Immunol, Lima, Peru
[28] Natl Univ Singapore Hosp, Dept Paediat, Singapore 117548, Singapore
[29] Karolinska Univ Hosp, Astrid Lindgren Childrens Hosp, Stockholm, Sweden
[30] Univ Virginia, Asthma & Allerg Dis Ctr, Charlottesville, VA USA
[31] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Pediat,Childhood Asthma Atopy Ctr, Seoul, South Korea
[32] Ain Shams Univ, Childrens Hosp, Pediat Allergy & Immunol Unit, Cairo, Egypt
[33] Chang Gung Childrens Hosp, Dept Pediat, Div Allergy Asthma & Rheumatol, Tao Yuan, Taiwan
[34] Univ Wisconsin, Dept Pediat, Sch Med & Publ Hlth, Madison, WI USA
[35] Erasmus Univ, Sophia Childrens Hosp, Med Ctr, Dept Pediat, Rotterdam, Netherlands
[36] Hacettepe Univ, Sch Med, Ihsan Dogramaci Childrens Hosp, Pediat Allergy & Asthma Unit, Ankara, Turkey
[37] Int Union TB & Lung Dis, Algiers, Algeria
[38] Univ Stellenbosch, Tygerberg Childrens Hosp, Dept Paediat & Child Hlth, Cape Town, South Africa
[39] Med Univ Lodz, Barlicki Univ Hosp, Dept Med 2, Lodz, Poland
[40] Charite, Dept Pediat Pneumol & Immunol, D-13353 Berlin, Germany
[41] Univ S Florida, Div Allergy Immunol, Tampa, FL USA
[42] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Pediat,Environm Hlth Ctr, Seoul, South Korea
[43] Univ Colorado Denver, Sch Med, Denver, CO USA
[44] Natl Jewish Hlth, Dept Pediat, Denver, CO USA
[45] Ullevaal Univ Hosp, Dept Paediat, Woman & Child Div, Oslo, Norway
[46] Gunma Univ, Kita Kanto Allergy Inst, Gunma, Japan
[47] Univ Gothenburg, Krefting Res Ctr, Gothenburg, Sweden
[48] Childrens Hosp La Fe, Pediat Allergy Unit, Valencia, Spain
[49] Lakeside Med Ctr & Hosp, Bangalore, Karnataka, India
[50] Nippon Med Sch, Dept Pediat, Div Allergy & Immunol, Tokyo 113, Japan
基金
美国国家卫生研究院; 美国国家科学基金会; 瑞士国家科学基金会;
关键词
asthma; children; consensus; guidelines; wheeze; INHALED FLUTICASONE PROPIONATE; NITRIC-OXIDE MEASUREMENTS; ACTING BETA-AGONISTS; HOUSE-DUST MITE; LONG-TERM; AIRWAY HYPERRESPONSIVENESS; PRESCHOOL-CHILDREN; ALLERGEN IMMUNOTHERAPY; PRIMARY PREVENTION; PERSISTENT ASTHMA;
D O I
10.1111/j.1398-9995.2012.02865.x
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Asthma is the most common chronic lower respiratory disease in childhood throughout the world. Several guidelines and/or consensus documents are available to support medical decisions on pediatric asthma. Although there is no doubt that the use of common systematic approaches for management can considerably improve outcomes, dissemination and implementation of these are still major challenges. Consequently, the International Collaboration in Asthma, Allergy and Immunology (iCAALL), recently formed by the EAACI, AAAAI, ACAAI, and WAO, has decided to propose an International Consensus on (ICON) Pediatric Asthma. The purpose of this document is to highlight the key messages that are common to many of the existing guidelines, while critically reviewing and commenting on any differences, thus providing a concise reference. The principles of pediatric asthma management are generally accepted. Overall, the treatment goal is disease control. To achieve this, patients and their parents should be educated to optimally manage the disease, in collaboration with healthcare professionals. Identification and avoidance of triggers is also of significant importance. Assessment and monitoring should be performed regularly to re-evaluate and fine-tune treatment. Pharmacotherapy is the cornerstone of treatment. The optimal use of medication can, in most cases, help patients control symptoms and reduce the risk for future morbidity. The management of exacerbations is a major consideration, independent of chronic treatment. There is a trend toward considering phenotype-specific treatment choices; however, this goal has not yet been achieved.
引用
收藏
页码:976 / 997
页数:22
相关论文
共 140 条
[1]  
Ait-Khaled N., 2008, Management of asthma: a guide to the essentials of good clinical practice
[2]   A pediatric asthma management program in a low-income setting resulting in reduced use of health service for acute asthma [J].
Andrade, W. C. C. ;
Camargos, P. ;
Lasmar, L. ;
Bousquet, J. .
ALLERGY, 2010, 65 (11) :1472-1477
[3]  
[Anonymous], 2011, From the Global Strategy for Asthma Management and Prevention
[4]  
[Anonymous], 2007, EXPERT PANEL REPORT
[5]  
[Anonymous], 2009, GLOB STRAT DIAGN MAN
[6]   Diagnosis and treatment of asthma in childhood: a PRACTALL consensus report [J].
Bacharier, L. B. ;
Boner, A. ;
Carlsen, K. -H. ;
Eigenmann, P. A. ;
Frischer, T. ;
Goetz, M. ;
Helms, P. J. ;
Hunt, J. ;
Liu, A. ;
Papadopoulos, N. ;
Platts-Mills, T. ;
Pohunek, P. ;
Simons, F. E. R. ;
Valovirta, E. ;
Wahn, U. ;
Wildhaber, J. .
ALLERGY, 2008, 63 (01) :5-34
[7]   Classifying asthma severity in children - Mismatch between symptoms, medication use, and lung function [J].
Bacharier, LB ;
Strunk, RC ;
Mauger, D ;
White, D ;
Lemanske, RF ;
Sorkness, CA .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2004, 170 (04) :426-432
[8]   Development and comorbidity of eczema, asthma and rhinitis to age 12-data from the BAMSE birth cohort [J].
Ballardini, N. ;
Kull, I. ;
Lind, T. ;
Hallner, E. ;
Almqvist, C. ;
Ostblom, E. ;
Melen, E. ;
Pershagen, G. ;
Lilja, G. ;
Bergstrom, A. ;
Wickman, M. .
ALLERGY, 2012, 67 (04) :537-544
[9]   DRUG-THERAPY - INHALED GLUCOCORTICOIDS FOR ASTHMA [J].
BARNES, PJ .
NEW ENGLAND JOURNAL OF MEDICINE, 1995, 332 (13) :868-875
[10]   Twelve-year survey of fatal reactions to allergen injections and skin testing: 1990-2001 [J].
Bernstein, DI ;
Wanner, M ;
Borish, L ;
Liss, GM .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2004, 113 (06) :1129-1136