Increased glucocorticoid receptor-β expression, but not decreased histone deacetylase 2, in severe asthma

被引:29
作者
Bergeron, C
Fukakusa, M
Olivenstein, R
Lemiere, C
Shannon, J
Ernst, P
Martin, JG
Hamid, Q
机构
[1] McGill Univ, Meakins Christie Labs, Montreal, PQ H2X 2P2, Canada
[2] McGill Univ, Div Resp, Montreal, PQ H3A 2T5, Canada
[3] Univ Montreal, Hop Sacre Coeur, Montreal, PQ, Canada
关键词
D O I
10.1016/j.jaci.2005.12.1344
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:703 / 705
页数:3
相关论文
共 10 条
  • [1] American Thoracic Society, 2000, AM J RESP CRIT CARE, V162, P2341
  • [2] GLUCOCORTICOID RECEPTOR-BETA, A POTENTIAL ENDOGENOUS INHIBITOR OF GLUCOCORTICOID ACTION IN HUMANS
    BAMBERGER, CM
    BAMBERGER, AM
    DECASTRO, M
    CHROUSOS, GP
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1995, 95 (06) : 2435 - 2441
  • [3] Christodoulopoulos P, 2000, J ALLERGY CLIN IMMUN, V106, P479
  • [4] Oral corticosteroids decrease eosinophil and CC chemokine expression but increase neutrophil, IL-8, and IFN-γ-inducible protein 10 expression in asthmatic airway mucosa
    Fukakusa, M
    Bergeron, C
    Tulic, MK
    Fiset, PO
    Al Dewachi, O
    Laviolette, M
    Hamid, Q
    Chakir, J
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2005, 115 (02) : 280 - 286
  • [5] Increased glucocorticoid receptor β in airway cells of glucocorticoid-insensitive asthma
    Hamid, QA
    Wenzel, SE
    Hauk, PJ
    Tsicopoulos, A
    Wallaert, B
    Lafitte, JJ
    Chrousos, GP
    Szefler, SJ
    Leung, DYM
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1999, 159 (05) : 1600 - 1604
  • [6] Expression and activity of histone deacetylases in human asthmatic airways
    Ito, K
    Caramori, G
    Lim, S
    Oates, T
    Chung, KF
    Barnes, PJ
    Adcock, IM
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2002, 166 (03) : 392 - 396
  • [7] Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients
    Matthews, JG
    Ito, K
    Barnes, PJ
    Adcock, IM
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2004, 113 (06) : 1100 - 1108
  • [8] High constitutive glucocorticoid receptor β in human neutrophils enables them to reduce their spontaneous rate of cell death in response to corticosteroids
    Strickland, I
    Kisich, K
    Hauk, PJ
    Vottero, A
    Chrousos, GP
    Klemm, DJ
    Leung, DYM
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2001, 193 (05) : 585 - 593
  • [9] Bronchoscopic evaluation of severe asthma - Persistent inflammation associated with high dose glucocorticoids
    Wenzel, SE
    Szefler, SJ
    Leung, DYM
    Sloan, SI
    Rex, MD
    Martin, RJ
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1997, 156 (03) : 737 - 743
  • [10] 1987, AM REV RESP DIS, V136, P225