Current concepts - Microarray analysis and tumor classification

被引:282
作者
Quackenbush, John
机构
[1] Dana Farber Canc Inst, Boston, MA 02115 USA
[2] Harvard Univ, Sch Publ Hlth, Boston, MA 02115 USA
关键词
D O I
10.1056/NEJMra042342
中图分类号
R5 [内科学];
学科分类号
1002 [临床医学]; 100201 [内科学];
摘要
Microarray analysis is a tool that can be used to compare the RNA profile of one cancer with that of another and to determine the diagnosis and prognosis of cancer. This article provides a description of the gene-expression microarray - how it works, how the data are analyzed, and the strengths and limitations of this tool. Copyright © 2006 Massachusetts Medical Society.
引用
收藏
页码:2463 / 2472
页数:10
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