The Heck reaction of electron-rich olefins with regiocontrol by hydrogen-bond donors

被引：108

作者：

Mo, Jun ^{[1
]}

Xiao, Jianliang ^{[1
]}

机构：

[1] Univ Liverpool, Dept Chem, Liverpool Ctr Mat & Catalysis, Liverpool L69 7ZD, Merseyside, England

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 25期

关键词：

Heck reaction; homogeneous catalysis; hydrogen bonding; ionic liquids; regioselectivity;

D O I：

10.1002/anie.200600799

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

No salt please: Halide scavengers AgOTf and TlOAc are not required for the Heck coupling of electron-rich olefins with aryl bromides and chlorides. Using ammonium additives, these reactions can be carried out in either an imidazolium ionic liquid or a common molecular solvent, thus furnishing 1,1′- disubstituted olefins in high yields with excellent regioselectivities. (Chemical Equation Presented). © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：4152 / 4157

页数：6

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