Secondary hemophagocytic lymphohistiocytosis in Turkish children

被引：45

作者：

Gurgey, A ^{[1
]}

Secmeer, G

Tavil, B

Ceyhan, M

Kushkonmaz, B

Cengiz, B

Ozen, H

Kara, A

Cetin, M

Gumruk, F

机构：

[1] Hacettepe Univ, Pediat Hematol Unit, Ankara, Turkey

[2] Hacettepe Univ, Pediat Infect Dis Unit, Ankara, Turkey

[3] Hacettepe Univ, Pediat Gastroenterol Unit, Dept Pediat, Fac Med, Ankara, Turkey

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2005年 / 24卷 / 12期

关键词：

secondary hemophagocytic lyrnphohistiocytosis; frequency of hemophagocytic lymphohistiocytosis; bacterial infection; viral infection; cytomegalovirus infection;

D O I：

10.1097/01.inf.0000190043.48182.31

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Between January 1998 and January 2005, a total of 18 children 2 weeks-72 months of age were diagnosed as having secondary hemophagocytic lymphohistiocytosis. The frequency of secondary hemophagocytic lymphohistiocytosis among total hospitalized patients during this period was 0.05% (18 of 34,250). Of the 18 patients, 8 (44.5%) had bacterial infections; cytomegalovirus and Epstein-Barr virus infections were present in 5 (28%) and 1 (5.5%), patient, respectively. Leishmaniasis was diagnosed in 2 patients (11%), and herpes simplex virus was diaganosed in 2 patients (11%). Six patients died during treatment, and 1 patient was lost to follow-up. The survival rate was 61%.

引用

页码：1116 / 1117

页数：2

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