Antibacterial Strategies from the Sea: Polymer-Bound Cl-Catechols for Prevention of Biofilm Formation

被引:105
作者
Garcia-Fernandez, Luis [1 ]
Cui, Jiaxi [1 ]
Serrano, Cristina [1 ]
Shafiq, Zahid [1 ]
Gropeanu, Radu A. [1 ]
San Miguel, Veronica [1 ]
Ramos, Jagoba Iturri [1 ]
Wang, Miao [1 ]
Auernhammer, Gunther K. [1 ]
Ritz, Sandra [1 ]
Golriz, Ali A. [1 ]
Berger, Ruediger [1 ]
Wagner, Manfred [1 ]
del Campo, Aranzazu [1 ]
机构
[1] Max Planck Inst Polymer Res, D-55128 Mainz, Germany
关键词
biomimetics; catechols; antibacterial strategies; DOPA; SURFACE-CHEMISTRY; MUSSEL; TOXICITY;
D O I
10.1002/adma.201203362
中图分类号
O6 [化学];
学科分类号
070301 [无机化学];
摘要
Inspired by the amino acid 2-chloro4,5-dihydroxyphenylalanine (Cl-DOPA), present in the composition of the proteinaceous glue of the sandcastle worm Phragmatopoma californica, a simple strategy is presented to confer antifouling properties to polymer surfaces using (but not releasing) a bioinspired biocide. Cl-Dopamine is used to functionalize polymer materials and hydrogel films easily, to prevent biofilm formation on them.
引用
收藏
页码:529 / 533
页数:5
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