Physiological regulation of blood pressure and kidney function by guanylyl cyclase isoforms

被引：19

作者：

Kishimoto, I

Garbers, DL

机构：

[1] UNIV TEXAS, SW MED CTR, HOWARD HUGHES MED INST, DALLAS, TX 75235 USA

[2] UNIV TEXAS, SW MED CTR, DEPT PHARMACOL, DALLAS, TX 75235 USA

来源：

CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION | 1997年 / 6卷 / 01期

关键词：

D O I：

10.1097/00041552-199701000-00011

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Guanylyl cyclase isoforms can serve as receptors for Various molecules including atrial natriuretic peptide, brain natriuretic peptide, C-type natriuretic peptide and nitric oxide, It has been speculated these signaling pathways are important regulators of cardiovascular and renal physiology, Within the past year, gene targeting in particular has strengthened this speculation, suggesting critical roles oi guanylyl cyclase receptors in both the chronic and acute regulation of blood pressure.

引用

页码：58 / 63

页数：6

共 48 条

[1] NITRIC OXIDE-DEPENDENT LONG-TERM POTENTIATION IS BLOCKED BY A SPECIFIC INHIBITOR OF SOLUBLE GUANYLYL CYCLASE [J].